Effects of standardized Cannabis sativa extract and ionizing radiation in melanoma cells in vitro
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چکیده
منابع مشابه
Standardized Cannabis sativa extract attenuates tau and stathmin gene expression in the melanoma cell line
Objective(s): Metastasis is the main cause of death in patients with melanoma. Cannabis-based medicines are effective adjunctive drugs in cancer patients. Tau and Stathmin proteins are the key proteins in cancer metastasis. Here we have investigated the effect of a standardized Cannabis sativa extract on cell migration and Tau and Stathmin gene expression in the melanoma cell line. Materials an...
متن کاملStandardized Cannabis sativa extract attenuates tau and stathmin gene expression in the melanoma cell line
Objectives Metastasis is the main cause of death in patients with melanoma. Cannabis-based medicines are effective adjunctive drugs in cancer patients. Tau and Stathmin proteins are the key proteins in cancer metastasis. Here we have investigated the effect of a standardized Cannabis sativa extract on cell migration and Tau and Stathmin gene expression in the melanoma cell line. Materials and...
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Background: Quercetin has been reported to modulate cell proliferation and apoptosis. The present study aimed at identifying whether treatment of ionizing radiation (IR) combined with quercetin induces apoptosis in HepG2 cells. Materials and Methods: HepG2 cells were plated at an appropriate density according to each experimental scale and irradiated with 1, 5 and 10 Gy gamma-rays from a 60Co s...
متن کاملInhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol.
PURPOSE Colon cancer is a major public health problem. Cannabis-based medicines are useful adjunctive treatments in cancer patients. Here, we have investigated the effect of a standardized Cannabis sativa extract with high content of cannabidiol (CBD), here named CBD BDS, i.e. CBD botanical drug substance, on colorectal cancer cell proliferation and in experimental models of colon cancer in viv...
متن کاملAqueous Extract of Nigella sativa Seeds Suppresses Testicular Steroidogenesis In Mice Leydig Cells, in vitro
Nigella sativa (black seed) is an important medicinal herb with folkloric use in wide range of diseases. It is well studied for its biological activities. However, there is limited information regarding its effect on the male reproductive system. This study describes the effect of the aqueous extract of N. sativa (NSE) on testicular steroidogenesis from mice Leydig cells in vitro . Mice tes...
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ژورنال
عنوان ژورنال: Journal of Cancer Research and Therapeutics
سال: 2018
ISSN: 0973-1482
DOI: 10.4103/jcrt.jcrt_1394_16